Latest Articles

Latest Articles have been peer-reviewed and accepted, which are not yet assigned to volumes/issues, but are citable by Digital Object Identifier (DOI).
Shionone protects cerebral ischemic injury via alleviating microglia-mediated neuroinflammation
XU Lushan, LI Chenggang, ZHAO ChenChen, WANG Zibu, ZHANG Zhi, SHU Xin, CAO Xiang, XIA Shengnan, BAO Xinyu, SHAO Pengfei, XU Yun
DOI: 10.1016/S1875-5364(25)60812-0
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Emd-D inhibited ovarian cancer progression via PFKFB4-dependent glycolysis and apoptosis
ZHAO Xin, CHEN Chao, FENG Xuefei, LEI Haoqi, QI Lingling, ZHANG Hongxia, XU Haiying, WAN Jufeng, ZHANG Yan, YANG Baofeng
DOI: 10.1016/S1875-5364(24)60663-1
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Ustusolate E and 11α-hydroxy-ustusolate E induce apoptosis in cancer cell lines by regulating the PI3K/AKT/mTOR and p-53 pathways
Rehmutulla Mewlude, ZHANG Sitian, YIN Jie, HUANG Jianzheng, XIAO Yang, HU Zhengxi, TONG Qingyi, ZHANG Yonghui
DOI: 10.1016/S1875-5364(24)60644-8
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Neuroprotective and antidiabetic lanostane-type triterpenoids from the fruiting bodies of Ganoderma theaecolum
GUO Jiaocen, YANG Li, DAI Luting, MA Qingyun, YAN Jiaoyang, XIE Qingyi, WU Yougen, DAI Haofu, ZHAO Youxing
DOI: 10.1016/S1875-5364(24)60698-9
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New acylphloroglucinol-sesquiterpenoid adducts with antiviral activities from Dryopteris atrata
ZHANG Jihui, WANG Jinghao, TANG Wei, SHEN Xi, CHEN Jinlin, OU Huilin, SITU Qianyi, LI Yaolan, WANG Guocai, ZHANG Yubo, CHEN Nenghua
DOI: 10.1016/S1875-5364(24)60620-5
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Zishen Huoxue decoction alleviates ischemic myocardial injury via Sirt5-β-tubulin mediated synergistic mechanism of "mitophagy-unfolded protein response" and mitophagy
CHANG Xing, ZHOU Siyuan, HUANG Yu, LIU Jinfeng, WANG Yanli, GUAN Xuanke, WU Qiaomin, LIU Zhiming, LIU Ruxiu
DOI: 10.1016/S1875-5364(24)60633-3
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Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway
LI Guohui, GUAN Yueqin, XU Lintao, PENG Guangcheng, HAN Qingtong, WANG Tian, XU Zhenpeng, WEN Xuesen, LOU Hongxiang, SHEN Tao
DOI: 10.1016/S1875-5364(24)60612-6
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Host-Microbe Co-metabolism System as Potential Targets: the Promising Way for Natural Medicine to Treat Atherosclerosis
Wang Yun, Zhou Ziwei, Hao Haiping, Cao Lijuan
DOI: 10.1016/S1875-5364(24)60749-1
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Advancements and Applications in Radiopharmaceutical Therapy
Wang Shiya, Cao Mingyi, Chen Yifei, Lin Jingjing, Li Jiahao, Wu Xinyu, Dai Zhiyue, Pan Yuhan, Liu Xiao, Liu Xian, Lin Liang-Ting, Wu Jianbing, Liu Ji, Zhong Qifeng, Yuan Zhenwei
DOI: 10.1016/S1875-5364(24)60747-8
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Buqi-Tongluo Decoction inhibits osteoclastogenesis and alleviates bone loss in ovariectomized rats by attenuating NFATc1, MAPK, NF-κB signaling
Li Yongxian, Yuan Jinbo, Deng Wei, Li Haishan, Lin Yuewei, Yang Jiamin, Chen Kai, Qiu Heng, Wang Ziyi, Kuek Vincent, Wang Dongping, Zhang Zhen, Mai Bin, Shao Yang, Kang Pan, Qin Qiuli, Li Jinglan, Guo Huizhi, Ma Yanhuai, Guo Danqing, Mo Guoye, Fang Yijing, Tan Renxiang, Zhan Chenguang, Liu Teng, Gu Guoning, Yuan Kai, Tang Yongchao, Liang De, Xu Liangliang, Xu Jiake, Zhang Shuncong
DOI: 10.1016/S1875-5364(24)60602-3
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Leveraging Microbial Natural Products for Pharmaceutical Innovation: A Vision of Inspiration and Future Prospects
YANG Jun-Biao, WANG Ji-Wen, LIU Meng-Qun, ZHOU Xu-Zhe, Feng Dong, JIANG Han-Xiang, LIU Xin-Na, Chen Lu, WANG Ying
DOI: 10.1016/S1875-5364(24)60713-2
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Metabolic Insights into Gut Microbiota in the Pharmacology of Natural Medicines (Accepted)
Chen Zixin, Zhou Junchi, Xie Hao, Zheng Xiao, Hao Haiping
DOI: 10.1016/S1875-5364(24)60745-4
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A comprehensive review on wedelolactone: natural sources, total synthesis, and pharmacological activities
Cai Haiping, Wu Yue, Zhang Xiaojin
DOI: 10.1016/S1875-5364(24)60733-8
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Ent-pimarane and ent-kaurane diterpenoids from Siegesbeckia pubescens and their anti-endothelial damage effect in diabetic retinopathy
Liu Mengjia, Luo Tingting, Li Rongxian, Yin Wenying, Yang Fengying, Ge Di, Liu Na
DOI: 10.1016/S1875-5364(24)60580-7
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Xanthones from Garcinia pedunculata and Garcinia nujiangensis and their anti-inflammatory activity
Fan Xiaojie, Jia Yufeng, Guo Jiaxin, Yang Jinyuan, Li Dahong, Hua Huiming
DOI: 10.1016/S1875-5364(24)60651-5
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Research progress in methods of acquisition, structure elucidation and quality control of Chinese herbal polysaccharides
Wang Tingting, Zhu Baojie, Zhao Jing, Li Shaoping
DOI: 10.1016/S1875-5364(24)60696-5
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Nigella sativa L. seed extract alleviates oxidative stress-induced cellular senescence and dysfunction in melanocytes
Niu Ben, An Xiaohong, Chen Yongmei, He Ting, Zhan Xiao, Zhu Xiuqi, Ping Fengfeng, Zhang Wei, Zhou Jia
DOI: 10.1016/S1875-5364(24)60645-X
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Tianxiangdan alleviates myocardial ischemia reperfusion-induced ferroptosis through the activation of ERα
Yue Yuan-Jia, Li Yu, Rong Xing, Ji Zhao, Wang Hui-Min, Chen Liang, Jiang Lin
DOI: 10.1016/S1875-5364(24)60613-8
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Expanding molecular diversity of RiPP natural products by radical SAM enzymes: recent advances and mechanistic insights
Feng Jiawei, Mo Jiarong, Hemu Xinya
DOI: 10.1016/S1875-5364(24)60732-6
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General expert consensus on application of network pharmacology in the research and development of new traditional Chinese medicine drugs
LI Shao, XIAO Wei
DOI: 10.1016/S1875-5364(25)60802-8
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Combination of Astragalus-Salvia and Ophiopogon-Dendrobium herb pairs alleviates Sjögren’s Syndrome via inhibiting the JAK1/STAT3 and PI3K/AKT pathways in NOD/Ltj mice
SUN Peng, ZHU Li-Li, YU Yang, HU Si-Jing, SHAN Meng-Yi, ZHAO Xuan, WANG Xin-Chang, ZHANG Qiao-Yan, QIN Lu-Ping
DOI: 10.1016/S1875-5364(24)60743-0
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Discovery of fernane type triterpenoids from Diaporthe discoidispora by using genome mining and HSQC-based SMART technology
WANG Yajing, LI Yongfu, DONG Yan, YU Chunyan, LIU Chengwei, LI Chang, SUN Yi, PEI Yuehu
DOI: 10.1016/S1875-5364(24)60628-X
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First-in-class drug Oroxylin A tables for treating hepatic and gastrointestinal disorders: From preclinical development to clinical research
Luo Chengju, Li Xuhong, Gao Yuan, Yang Junyi, Fang Weiming, Wei Libin
DOI: 10.1016/S1875-5364(24)60740-5
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Mass spectral database-based methodologies for the annotation and discovery of natural products
YANG Fengyao, LIANG Zeyuan, ZHAO Haoran, ZHENG Jiayi, LIU Lifang, SONG Huipeng, XIN Guizhong
DOI: 10.1016/S1875-5364(24)60739-9
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Natural endogenous material-based vehicles for delivery of macromolecular drugs
LU An, DU Kang, WANG Meng, ZHU Zehang, LEI Lei, SHI Yujie
DOI: 10.1016/S1875-5364(24)60738-7
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Research Progress of Natural Saccharides and Their Derivatives as Drug Delivery Materials
WEI Yuning, KONG Weiwen, LIU Wenjuan, DONG Zirong, YANG Peiheng, TAO Juan, WEI Zibo, YANG Jinlong, QI Jianping
DOI: 10.1016/S1875-5364(24)60737-5
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Stem-leaf saponins of Panax notoginseng attenuate experimental Parkinson’s disease progression in mice by inhibiting microglia-mediated neuroinflammation via P2Y2R/PI3K/AKT/NFκB signaling pathway
Wu Hui, Ni Chenyang, Zhang Yu, Song Yingying, Liu Longchan, Huang Fei, Shi Hailian, Wang Zhengtao, Wu Xiaojun
DOI: 10.1016/S1875-5364(24)60631-X
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Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu Kui, Wang Ling, PANG Tao
DOI: 10.1016/S1875-5364(25)60801-6
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Recent advances, strategies, and future perspectives of peptide-based drugs in clinical applications
Yang Qimeng, Hu Zhipeng, Jiang Hongyu, Wang Jialing, Han Han, Shi Wei, Qian Hai
DOI: 10.1016/S1875-5364(25)60800-4
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Pinelliae Rhizoma: a systematic review on botany, ethnopharmacology, phytochemistry, preclinical and clinical evidence
Liang Zuanji, Wei Jinchao, Chan Sioi, Zhang Siyuan, Xu Li, Shen Chenxiao, Zhong Zhangfeng, Wang Yitao
DOI: 10.1016/S1875-5364(24)60605-9
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Astragali Radix−Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance
LIN Pingping, CHEN Hong, CUI Zekun, YU Boyang, KOU Junping, LI Fang
DOI: 10.1016/S1875-5364(24)60593-5
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Amoenucles A−F, undescribed nucleoside derivatives with TNF-α inhibitory activities from Aspergillus amoenus TJ507
Zhang Yeting, Shi Zhengyi, Zhao Chunhua, Li Lanqin, Chen Ming, Cao Yunfang, Wang Fengqing, Tao Bo, Huang Xinye, Guo Jieru, Qi Changxing, Sun Weiguang, Zhang Yonghui
DOI: 10.1016/S1875-5364(24)60570-4
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Exploring the mechanism of Xiaoaiping Injection inhibiting autophagy in prostate cancer based on proteomics
ZHANG Qiuping, HUANG Qiuju, CHENG Zhiping, XUE Wei, LIU Shoushi, LIAO Yunnuo, LI Xiaolan, CHEN Xin, HAN Yaoyao, ZHU Dan, SU Zhiheng, YANG Xin, LUO Zhuo, GUO Hongwei
DOI: 10.1016/S1875-5364(24)60567-4
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Curvularin derivatives from hydrothermal vent sediment fungus Penicillium sp. HL-50 guided by molecular networking and their anti-inflammatory activity
YU Chunxue, XIA Zixuan, XU Zhipeng, TANG Xiyang, DING Wenjuan, WEI Jihua, TIAN Danmei, WU Bin, TANG Jinshan
DOI: 10.1016/S1875-5364(24)60551-0
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Zhongfeng Xingnao Liquid ameliorates post-stroke cognitive impairment through SIRT1/Nrf2/HO-1 pathway
Yang Wenqin, Wen Wen, Chen Hao, Zhang Haijun, Lu Yun, Wang Ping, Xu Shijun
DOI: 10.1016/S1875-5364(24)60604-7
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Recent advances in regulating the cell cycle through inhibiting CDKs for cancer treatment
CHEN Weijiao, ZHUANG Xujie, CHEN Yuanyuan, YANG Huanaoyu, SHEN Linhu, FENG Sikai, MIN Wenjian, YUAN Kai, YANG Peng
DOI: 10.1016/S1875-5364(24)60736-3
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The Role of 8-oxoG and Its Repair Systems in Liver Diseases Progression: Responsible Mechanisms and Promising Natural Products
ZHENG Ying, CHEN Jun-xin, LIU Ze, WANG Kai-bo, ZHANG Hao
DOI: 10.1016/S1875-5364(24)60735-1
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TCM network pharmacology: New perspective integrating network target with artificial intelligence and multi-modal multi-omics technologies
Wang Ziyi, Zhang Tingyu, Wang Boyang, Li Shao
DOI: 10.1016/S1875-5364(24)60734-X
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Azaphilone derivatives with RANKL-induced osteoclastogenesis inhibition from the mangrove endophytic fungus Diaporthe sp.
Lin Miaoping, Tan Yanhui, Lu Humu, Feng Yuyao, Li Min, Gao Chenghai, Liu Yonghong, Luo Xiaowei
DOI: 10.1016/S1875-5364(24)60730-2
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Emerging evidence of inter-organ interaction on drug transporters under liver injury
JIANG Ling, DENG Ying, MU Ruijing, FENG Wenke, LIU Xiaonan, LIU Li
DOI: 10.1016/S1875-5364(24)60729-6
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Advances in nanocarriers for targeted drug delivery and controlled drug release
WANG Yuqian, HUANG Renqi, FENG Shufan, MO Ran
DOI: 10.1016/S1875-5364(24)60728-4
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Pure drug nanomedicines - where we are?
Lai Yaoyao, Xie Bing, Zhang Wanting, He Wei
DOI: 10.1016/S1875-5364(24)60716-8
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Structurally novel tryptamine-derived alkaloids from the seeds of Peganum harmala and their antiviral activities against respiratory syncytial virus
WU Zhongnan, ZHANG Yubo, WANG Guocai, TANG Qing, LI Yaolan, XIE Xiaoqing, LIANG Yushen, CHENG Wen
DOI: 10.1016/S1875-5364(24)60708-9
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Ten New Lignans with Anti-inflammatory Activities from the Leaves of Illicium dunnianum
LI Ting, HE Xiaoqiang, PAN Dabo, ZENG Xiaochun, ZENG Siying, WANG Zhenzhong, YAO Xinsheng, XIAO Wei, LI Haibo, YU Yang
DOI: 10.1016/S1875-5364(24)60718-1
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TSZAF monomer combination downregulates the Wnt/β-catenin signaling pathway and inhibits neutrophil recruitment to prevent lung cancer metastasis
Yu Pan, Yao Jialiang, Zhang Long, Wang Yanhong, Lu Xinyi, Liu Jiajun, Que Zujun, Liu Yao, Ba Qian, Liu Jiwei, Wu Yan, Tian Jianhui
DOI: 10.1016/S1875-5364(24)60717-X
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Jasurolignoside from Ilex pubescens exerts a therapeutic effect on acute lung injury in vitro and in vivo by binding to TLR4
Han Shan, Vong Chi Teng, He Jia, Wang Qin-Qin, Fan Qiumei, Li Siyuan, Li Jilang, Liao Min, Yang Shilin, Yuan Renyikun, Gao Hongwei
DOI: 10.1016/S1875-5364(24)60715-6
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Research Progress on New Techniques and Methods for Identifying Active Ingredients in Traditional Chinese Medicine
ZHANG Jiaxin, ZHU Xinhao, ZHANG Chaofeng, ZHANG Wangning, TIAN Jiangwei
DOI: 10.1016/S1875-5364(24)60714-4
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Research progress of small-molecule natural medicines for the treatment of ischemic stroke
Liu Kui, Wang Ling, Pang Tao
DOI: 10.1016/S1875-5364(24)60712-0
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Combining label-free quantitative proteomics and 2D-DIGE to identify the potential targets of Sini decoction acting on myocardial infarction
Feng Fei, Zhang Weiyue, Cao Yan, Lv Diya, Chai Yifeng, Guo Dandan, Chen Xiaofei
DOI: 10.1016/S1875-5364(24)60711-9
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Discovery of Bioactive Polycyclic Polyprenylated Acylphloroglucinol from Hypericum patulum that Protects Against Hepatic Ischemia/Reperfusion Injury
TAO Bo, ZHAO Xiangli, SHI Zhengyi, LI Jie, DUAN Yulin, TAN Xiaosheng, CHEN Gang, QI Changxing, ZHANG Yonghui
DOI: 10.1016/S1875-5364(24)60710-7
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Structurally diverse terpenoids from Pseudotsuga brevifolia and their inhibitory effects against ACL and ACC1 enzymes
ZHOU Peng-Jun, ZHAO Ze-Yu, ZANG Yi, XIONG Juan, CHOO Yeun-Mun, LI Jia, HU Jin-Feng
DOI: 10.1016/S1875-5364(24)60709-0
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Profiling the chemical differences of diterpenoid alkaloids in different processed products of Aconiti Lateralis Radix Praeparata by UHPLC-LTQ-Orbitrap mass spectrometry combined with untargeted metabolomics and mass spectrometry imaging
YU Yang, YAO Changliang, ZHANG Jianqing, HUANG Yong, YAO Shuai, QU Hua, ZHANG Tong, GUO De-an
DOI: 10.1016/S1875-5364(24)60707-7
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Lingguizhugan decoction improves chronic heart failure by synergistically modulating β1-AR/Gs/GRKs/β-arrestin signaling bias
Guo Shuting, Xia Lei, Yang Songru, Liang Yueyang, Shan Xiaoli, Zhao Pei, Guo Wei, Zhang Chen, Xu Ming, Sun Ning, Lu Rong, Chen Huihua
DOI: 10.1016/S1875-5364(24)60705-3
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Recent advances in peptide-based therapy: Challenges, strategies and future perspectives
YANG Qimeng, HU Zhipeng, JIANG Hongyu, WANG Jialing, HAN Han, SHI Wei, QIAN Hai
DOI: 10.1016/S1875-5364(24)60697-7
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Natural products targeting NLRP3 inflammasome for metabolic dysfunction-associated fatty liver disease: The known unknowns
Meng Jiahui, Wang Qiqi, Wang Haopeng, Shen Xuange, Qin Tingting, Zhao Wen, Li Haixia, Yuan Ziqiao
DOI: 10.1016/S1875-5364(24)60695-3
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Dimeric sesquiterpenoids with anti-inflammatory activities from Inula britannica
Zhang Juan, Yan Jian-Kun, Dong Hong-Jun, Zhang Rui, Chang Jing, Feng Yan-Li, Xu Xin-Rong, Li Wei, Qiu Feng, Sun Cheng-Peng
DOI: 10.1016/S1875-5364(24)60692-8
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Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonistically modulating CCL18
Bi QianYu, Wang MengRan, Luo Li, Zhang BeiYing, Lv SiYuan, Wang ZengNa, Ji XuMing
DOI: 10.1016/S1875-5364(24)60691-6
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The transcriptomic-based disease network reveals synergistic therapeutic effect of total alkaloids from Coptis chinensis and total ginsenosides on type 2 diabetes mellitus
Chen Qian, Zhang Shuying, Jiang Xuanxi, Liao Jie, Shao Xin, Peng Xin, Wang Zheng, Lu Xiaoyan, Fan Xiaohui
DOI: 10.1016/S1875-5364(24)60689-8
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Facilitating microglial phagocytosis by which Jiawei Xionggui decoction alleviates cognitive impairment via TREM2-mediated Energy metabolic reprogramming
Wen Wen, Jie Chen, Junbao Xiang, Shiqi Zhang, Jingru Liu, Jie Wang, Ping Wang, Shijun Xu
DOI: 10.1016/S1875-5364(24)60688-6
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Isodons A-H, seco-abietane and abietane-type diterpenoids from Isodon lophanthoides: isolation, structural elucidation, and anticholestatic activity
Zhou Hui-Ling, Han Ming-Zhu, Nan Miao-Miao, Leng Ying-Rong, Huang Wei-Ming, Ye Sheng-Tao, Kong Ling-Yi, Xu Wen-Jun, Zhang Hao
DOI: 10.1016/S1875-5364(24)60686-2
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New tetrahydroanthraquinones and γ-butenolides from the fungus Auxarthron umbrinum DSM3193
Tian Ling, Liu Bingyu, Wei Qian, Zhang Chen, Shang Jiamin, Li Xiaoxue, Yang Xiuying, Wang Jinhua, Hu Youcai
DOI: 10.1016/S1875-5364(24)60684-9
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Diterpenoids and lignans from fossil Chinese medicinal succinum and their activity against renal fibrosis
Chen Ye-Fei, Wang Yun-Fei, Liu Yun-Yun, Yan Yong-Ming, Cheng Yong-Xian
DOI: 10.1016/S1875-5364(24)60683-7
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Bioactivity-guided discovery of antiviral templichalasins A‒C from the endophytic fungus Aspergillus templicola
CAI Teng, SUN Jingzu, CHEN Wenxuan, HE Qiang, CHEN Baosong, HE Yulong, ZHANG Peng, WEI Yanhong, LIU Hongwei, CAI Xiaofeng
DOI: 10.1016/S1875-5364(24)60682-5
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Deciphering the therapeutic potential and mechanisms of Artemisia argyit essential oil on flagellum-mediated Salmonella infections
Linlin Ding, Lei Xu, Na Hu, Jianfeng Wang, Jiazhang Qiu, Qingjie Li, Xuming Deng
DOI: 10.1016/S1875-5364(24)60703-X
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Diketopiperazines with anti-skin inflammation from marine-derived endophytic fungus Aspergillus sp. and configurational reassignment of aspertryptanthrins
Jin YANG, Xianmei XIONG, Lizhi GONG, Fengyu GAN, Hanling SHI, Bin ZHU, Haizhen WU, Xiujuan XIN, Lingyi KONG, Faliang AN
DOI: 10.1016/S1875-5364(24)60704-1
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Lirispirolides A–L, a new class of sesquiterpene‐monoterpene heterodimers with anti-neuroinflammatory activity from the rare medicinal plant Liriodendron chinense
HE Yu-Hang, LI Ke-Xin, WU Yu-Fei, JIN Ze-Xin, HU Jin-Feng, MAO Yi-Cheng, XIONG Juan
DOI: 10.1016/S1875-5364(24)60702-8
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Identification and biomimetic synthesis of iphionanes and cyperanes from Artemisia hedinii and their anti-hepatic fibrosis activity
LIU Xiaofei, WANG Xing, TANG Chunping, KE ChangQiang, HU Bintao, YAO Sheng, YE Yang
DOI: 10.1016/S1875-5364(24)60701-6
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(±)-Talapyrones A−F: Six pairs of dimeric polyketide enantiomers with unusual 6/6/6 and 6/6/6/5 ring systems from Talaromyces adpressus
Meijia Zheng, Xinyi Zhao, Chenxi Zhou, Hong Liao, Qin Li, Yuling Lu, Bingbing Dai, Weiguang Sun, Ying Ye, Chunmei Chen, Yonghui Zhang, Hucheng Zhu
DOI: 10.1016/S1875-5364(24)60699-0
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The prospect and underlying mechanisms of Chinese medicine in treating periodontitis
Aili Xing, Feng Wang, Jinzhong Liu, Yuan Zhang, Jingya He, Bin Zhao, Bin Sun
DOI: 10.1016/S1875-5364(24)60678-3
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A CYP80B enzyme from Stephania tetrandra enables the 3'-hydroxylation of N-methylcoclaurine and coclaurine in the biosynthesis of benzylisoquinoline alkaloids
Yao-Ting LI, Yu-Han FENG, Wan GUO, Yu GAO, Jia-Tao ZHANG, Lu YANG, Chun LEI, Yun KANG, Ya-Qin WANG, Xu-Dong QU, Jian-Ming HUANG
DOI: 10.1016/S1875-5364(24)60677-1
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Esculetin triggers ferroptosis via inhibition of Nrf2-xCT/GPx4 axis in hepatocellular carcinoma
QU Zhi-Xin, ZENG Jing, ZENG Lai-Feng, LI Xian-Mei, ZHANG Feng-Hua
DOI: 10.1016/S1875-5364(24)60676-X
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Structurally diverse sesquiterpenoids with anti-MDR cancer activity from Penicillium roqueforti
Shuyuan MO, Nanjin DING, Zhihong HUANG, Jun YAO, Weiguang SUN, Jianping WANG, Yonghui ZHANG, Zhengxi HU
DOI: 10.1016/S1875-5364(24)60675-8
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Salidroside inhibits osteoclast differentiation based on osteoblast-osteoclast interaction via HIF-1α pathway
Jin Yutong, Wang Yao, Wang Chuan, Zhang Lingling, Gao Dandan, Liu Haizhao, Cao Qingwen, Tian Chenchen, Bian Yuhong, Wang Yue
DOI: 10.1016/S1875-5364(24)60673-4
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Saponins from Aralia taibaiensis protect against brain ischaemia/reperfusion injuries by regulating the apelin/AMPK pathway
Zhengrong Li, Yuwen Liu, Kedi Liu, Xingru Tao, Naping Hu, Wangting Li, Jialin Duan
DOI: 10.1016/S1875-5364(24)60672-2
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Pristimerin induces Noxa-dependent apoptosis by activating the FoxO3a pathway in esophageal squamous cell carcinoma
Feng Mengyuan, Zhang Anjie, Wu Jingyi, Cheng Xinran, Yang Qingyu, Gong Yunlai, Hu Xiaohui, Ji Wentao, Yu Xianjun, Zhao Qun
DOI: 10.1016/S1875-5364(24)60670-9
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Evaluation of Pharmacokinetics and Metabolism of Three Marine-derived Piericidins for Guiding Drug Lead Selection
LIANG Weimin, LU Jindi, YU Ping, CAI Meiqun, XIE Danni, CHEN Xini, ZHANG Xi, TIAN Lingmin, YAN Liyan, LAN Wenxun, LIU Zhongqiu, ZHOU Xuefeng, TANG Lan
DOI: 10.1016/S1875-5364(24)60669-2
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Naturally occurring seco- and nor-polycyclic polyprenylated acylphloroglucinols: Distribution, structural diversity, and biological activity
Duan Yulin, Tang Ying, Qi Changxing, Zhang Yonghui
DOI: 10.1016/S1875-5364(24)60668-0
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Novel Araucarene Diterpenes from Agathis Dammara Exert Hypoglycemic Activity by Promoting Pancreatic β Cells Regeneration and Glucose Uptake
YU Zhewei, ZHANG Yi, WANG Wenhui, WU XinYi, LIU Shunzhi, BIN Yanlin, LI Hongsheng, CAI Bangping, WANG Zheng, FANG Meijuan, QI Rong, LI Mingyu, QIU Yingkun
DOI: 10.1016/S1875-5364(24)60667-9
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A quinolinyl analog of resveratrol improves neuronal damage after ischemic stroke by promoting Parkin-mediated mitophagy
Qingqi Meng, Yan Mi, Libin Xu, Yeshu Liu, Dong Liang, Yongping Wang, Feng Wang, Yueyang Liu, Guoliang Chen, Yue Hou
DOI: 10.1016/S1875-5364(24)60666-7
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Magnolol inhibits appetite and causes visceral fat loss through GDF-15 by activating transcription factor 4-CCAAT enhancer binding protein γ-mediated endoplasmic reticulum stress responses
Cheng Ke-ru, Zhou Yan-yun, Hao Yi-long, Wu Sheng-yun, Wang Nan-ping, Zhang Peng, Wang Yin-fang
DOI: 10.1016/S1875-5364(24)60665-5
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Ziyuglycoside II suppressed the progression of osteosarcoma by coordinating estrogen-related receptor gamma and p53 signaling pathway
DU Hang, WU Dongjin, ZHANG Tianyu, ZHONG Ying, WU Kaiyi, GUO Xin, SHENG Lisong, HUANG Nana, GAO Chunzheng, SUN Rong
DOI: 10.1016/S1875-5364(24)60664-3
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Diphenylemestrins A−E: Diketopiperazine-Diphenyl Ether Hybrids from Aspergillus nidulans
Fu Aimin, Li Qin, Xiao Yang, Dong Jiaxin, Peng Yuanyang, Chen Yu, Tong Qingyi, Chen Chunmei, Zhang Yonghui, Zhu Hucheng
DOI: 10.1016/S1875-5364(24)60662-X
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Metabolomics as An Emerging Tool for the Pharmacological and Toxicological Studies on Aconitum Alkaloids
Ding Han, Liu Yamin, Wang Sifan, Mei Yuqi, Li Linnan, Xiong Aizhen, Wang Zhengtao, Yang Li
DOI: 10.1016/S1875-5364(24)60661-8
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Oroxylin A inhibits UVB-induced non-melanoma skin cancer by regulating XPA degradation
Renjie Dou, Jiarui Sun, Hang Yang, Yufen Zheng, Kang Yuan, Lei Qiang, Run Ma, Yunyao Liu
DOI: 10.1016/S1875-5364(24)60660-6
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Xiao-Huang-Qu-Dan Decoction alleviates ANIT-induced cholestatic liver injury by inhibiting JAK2/STAT3 pathway and regulating TH17/Treg
Tan Zhangkui, Chen Lifeng, Ye Zhiqin, Lu Qiping
DOI: 10.1016/S1875-5364(24)60658-8
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Five new meroterpenoids from Rhododendron anthopogonoides and their anti-inflammatory activity
LI Mengtian, KELSANG Norbu, ZHAO Yongqin, LI Wensen, ZHOU Feng, Pema, CUI Lu, BAO Xianjie, WANG Qian, FENG Xin, YANG Minghua
DOI: 10.1016/S1875-5364(24)60650-3
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Platycodon grandiflorus polysaccharides combined with hesperidin exerted the synergistic effect of relieving ulcerative colitis in mice by modulating PI3K/AKT and JAK2/STAT3 signaling pathways
Liu Yang, Sun Quanwei, Xu Xuefei, Li Mengmeng, Gao Wenheng, Li Yunlong, Yang Ye, Yin Dengke
DOI: 10.1016/S1875-5364(24)60647-3
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NUMB endocytic adaptor protein mediates the anti-hepatic fibrosis effect of artesunate by inducing senescence in hepatic stellate cells
Qiu Yang-ling, Li Yu-jia, Fu Qiu-yu, Li Meng-ran, Wang Ying-qian, Shen Min, Gao Yuan-yuan, Ji Shu-fan, Wang Shu-qi, Shao Jiang-juan, Zhang Feng, Xu Xue-fen, Wang Fei-xia, Zhang Zi-li, Zheng Shi-zhong
DOI: 10.1016/S1875-5364(24)60634-5
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Withanolide derivatives from Physalis angulata var. villosa and their cytotoxic activities
Wang Peng, Yang Jue, Zhang Yu, Jin Jun, Chen Mei-Jun, Hao Xiao-Jiang, Yuan Chun-Mao, Yi Ping
DOI: 10.1016/S1875-5364(24)60625-4
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Andrographolide sulfonate alleviates rheumatoid arthritis by inhibiting glycolysis-mediated activation of PI3K/AKT to restrain Th17 differentiation
Chunhong Jiang, Xi Zeng, Jia Wang, Xiaoqian Wu, Lijuan Song, Ling Yang, Ze Li, Ning Xie, Xiaomei Yuan, Zhifeng Wei, Yi Guan
DOI: 10.1016/S1875-5364(24)60627-8
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Natural Diosmin Alleviating Obesity and NAFLD by Regulating AMPK Pathway
Liu Can, Hao Siyu, Zhang Mengdi, Wang Xueyu, Chu Baiwang, Wen Tingjie, Dang Ruoyu, Sun Hua
DOI: 10.1016/S1875-5364(24)60609-6
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Protective effect of capsaicin on alleviating ethanol-induced oxidative gastric mucosal injury via mediation of the CCR4/Src/p47phox signaling pathway both in vitro and in vivo
Yang Zhiru, Guo Haolin, Zhang Pengfei, Liu Kairui, Ba Junli, Bai Xue, Shama Shiti, Zhang Bo, Gao Xiaoning, Kang Jun
DOI: 10.1016/S1875-5364(24)60584-4
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Harmonizing tradition and technology: liposomal nanocarriers unlocking the power of natural herbs in Traditional Chinese Medicine
SHAW IBRAHIM, ARYEE AARON ALBERT, ALI YIMER SEID, BOAFO GEORGE FRIMPONG, TIAN JINGJING, MLAMBO RONALD, TAN SONGWEN, CHEN CHUANPIN
DOI: 10.1016/S1875-5364(24)60552-2
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Kai-Xin-San Alleviated Neurodegeneration by Reducing Neuroinflammation and Rebalancing Intestinal Flora in APP/PS1 mice
Li Meixian, Li Jiaqi, Wei Dongyun, Wang Qi, Jian Wenxuan
DOI: 10.1016/S1875-5364(23)60513-8
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Tu-Xian decoction ameliorates diabetic cognitive impairment by inhibiting DAPK-1
DOI: 10.1016/S1875-5364(23)60406-6
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Isolation and Biological Activity of Seven New Drimane-Type Sesquiterpenoids from an Earwig-Associated Aspergillus sp. NF2396
Salman Khan, ZHU Hong-Jie, SUN Zi-Qian, Li Yi-Lin, WANG Lan, WANG Rong, GUO Zhi-Kai, JIAO Rui-Hua
DOI: 10.1016/S1875-5364(22)60207-3
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Liver metabonomics study on the protective effect of glycyrrhetinic acid against realgar-induced liver injury
Huo Taoguang, Fang Ying, Zhang Yinghua, Feng Cong, Jiang Hong
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