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        Expanding molecular diversity of ribosomally synthesized and post-translationally modified peptide (RiPP) natural products by radical S-adenosylmethionine (SAM) enzymes: recent advances and mechanistic insights
        Feng Jiawei, Mo Jiarong, Hemu Xinya
        2025, 23(3): 257-268. DOI: 10.1016/S1875-5364(25)60845-4
        Abstract FullText HTML PDF
        The prospect and underlying mechanisms of Chinese medicine in treating periodontitis
        Xing Aili, Wang Feng, Liu Jinzhong, Zhang Yuan, He Jingya, Zhao Bin, Sun Bin
        2025, 23(3): 269-285. DOI: 10.1016/S1875-5364(25)60842-9
        Abstract FullText HTML PDF
        Recent advances in regulating the cell cycle through inhibiting CDKs for cancer treatment
        Chen Weijiao, Zhuang Xujie, Chen Yuanyuan, Yang Huanaoyu, Shen Linhu, Feng Sikai, Min Wenjian, Yuan Kai, Yang Peng
        2025, 23(3): 286-298. DOI: 10.1016/S1875-5364(25)60846-6
        Abstract FullText HTML PDF
        Saponins from Aralia taibaiensis protect against brain ischemia/reperfusion injuries by regulating the apelin/AMPK pathway
        Li Zhengrong, Liu Yuwen, Liu Kedi, Tao Xingru, Hu Naping, Li Wangting, Duan Jialin
        2025, 23(3): 299-310. DOI: 10.1016/S1875-5364(25)60841-7
        Abstract FullText HTML PDF
        Zishen Huoxue decoction (ZSHX) alleviates ischemic myocardial injury (MI) via Sirt5-β-tubulin mediated synergistic mechanism of "mitophagy-unfolded protein response" and mitophagy
        Chang Xing, Zhou Siyuan, Huang Yu, Liu Jinfeng, Wang Yanli, Guan Xuanke, Wu Qiaomin, Liu Zhiming, Liu Ruxiu
        2025, 23(3): 311-321. DOI: 10.1016/S1875-5364(25)60838-7
        Abstract FullText HTML PDF
        NUMB endocytic adaptor protein (NUMB) mediates the anti-hepatic fibrosis effect of artesunate (ART) by inducing senescence in hepatic stellate cells (HSCs)
        Qiu Yangling, Li Yujia, Li Mengran, Wang Yingqian, Shen Min, Shao Jiangjuan, Zhang Feng, Xu Xuefen, Wang Feixia, Zhang Zili, Zheng Shizhong
        2025, 23(3): 322-333. DOI: 10.1016/S1875-5364(25)60836-3
        Abstract FullText HTML PDF
        Magnolol inhibits appetite and causes visceral fat loss through Growth/differentiation factor-15 (GDF-15) by activating transcription factor 4-CCAAT enhancer binding protein γ-mediated endoplasmic reticulum stress responses
        Cheng Keru, Zhou Yanyun, Hao Yilong, Wu Shengyun, Wang Nanping, Zhang Peng, Wang Yinfang
        2025, 23(3): 334-345. DOI: 10.1016/S1875-5364(25)60835-1
        Abstract FullText HTML PDF
        Ustusolate E and 11α-Hydroxy-Ustusolate E induce apoptosis in cancer cell lines by regulating the PI3K/AKT/mTOR and p-53 pathways
        Rehmutulla Mewlude, Zhang Sitian, Yin Jie, Huang Jianzheng, Xiao Yang, Hu Zhengxi, Tong Qingyi, Zhang Yonghui
        2025, 23(3): 346-353. DOI: 10.1016/S1875-5364(25)60840-5
        Abstract FullText HTML PDF
        Ziyuglycoside II suppressed the progression of osteosarcoma by coordinating estrogen-related receptor gamma and p53 signaling pathway
        Du Hang, Wu Dongjin, Zhang Tianyu, Zhong Ying, Wu Kaiyi, Guo Xin, Sheng Lisong, Huang Nana, Gao Chunzheng, Sun Rong
        2025, 23(3): 354-367. DOI: 10.1016/S1875-5364(25)60847-8
        Abstract FullText HTML PDF
        Discovery of fernane-type triterpenoids from Diaporthe discoidispora using genome mining and HSQC-based SMART technology
        Wang Yajing, Li Yongfu, Dong Yan, Yu Chunyan, Liu Chengwei, Li Chang, Sun Yi, Pei Yuehu
        2025, 23(3): 368-376. DOI: 10.1016/S1875-5364(25)60837-5
        Abstract FullText HTML PDF
        New acylphloroglucinol-sesquiterpenoid adducts with antiviral activities from Dryopteris atrata
        Zhang Jihui, Wang Jinghao, Tang Wei, Shen Xi, Chen Jinlin, Ou Huilin, Situ Qianyi, Li Yaolan, Wang Guocai, Zhang Yubo, Chen Nenghua
        2025, 23(3): 377-384. DOI: 10.1016/S1875-5364(25)60839-9
        Abstract FullText HTML PDF