Abstract:
A pair of new tirucallane triterpenoid epimers, picraquassins M and N (
1 and
2 ), were isolated from the stems of
Picrasma quassioides (D. Don) Benn. Their structures were determined based on comprehensive spectroscopic and X-ray crystallographic analyses. In addition, their AChE inhibitory activity, cytotoxicity against five human tumour cell lines (SW480, MCF-7, HepG2, Hela, and PANC-1), and antimicrobial activity against two bacteria (
Staphylococcus. aureus 209P and
Escherichia coli ATCC0111) and two fungi (
Candida albicans FIM709 and
Aspergillus niger R330) were evaluated.
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