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Duo CAO, Li-Qing WANG, Xiao-Min HAN, Hui-Rui GUAN, Meng LEI, Ya-Hui WEI, Liang CHENG, Pei-Ming YANG, Zheng-Liang SUN, Wen GAO, Jia-Kun DAI. Two symmetrical unsaturated acids isolated from Viscum album[J]. Chinese Journal of Natural Medicines, 2019, 17(2): 145-148.
Citation: Duo CAO, Li-Qing WANG, Xiao-Min HAN, Hui-Rui GUAN, Meng LEI, Ya-Hui WEI, Liang CHENG, Pei-Ming YANG, Zheng-Liang SUN, Wen GAO, Jia-Kun DAI. Two symmetrical unsaturated acids isolated from Viscum album[J]. Chinese Journal of Natural Medicines, 2019, 17(2): 145-148.

Two symmetrical unsaturated acids isolated from Viscum album

  • Abstract: In the present study, two new acetylene conjugate compounds, dibutyl (2Z, 6Z)-octa-2, 6-dien-4-yne dioate ( 1 ), and dibutyl (2E, 6E)- octa-2, 6-dien-4-yne dioate ( 2 ), were isolated from the dry stem leaves of Viscum album, along with nine known compounds ( 3 - 11 ). Their structures were confirmed on the basis of spectroscopic data. Compounds 1 and 8 showed antioxidant activity against xanthine oxidase (XOD) and 1, 1-diphenyl-2-picrylhydrazyl radical 2, 2-diphenyl-1-(2, 4, 6-trinitrophenyl) hydroxyl (DPPH), with the IC50 of 1.22 and 1.33 μmol·L-1, and the SC50 of 4.34 and 8.22 μmol·L-1, respectively.

     

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