小蓟中一个新的大柱香波龙烷苷

A new megastigmane glycoside from the aerial parts of Cirsium setosum

摘要: 目的:研究小蓟的化学成分。方法:通过多种色谱手段进行化学成分的分离与纯化。结果:一个新的大柱香波龙烷苷和六个已知化合物被分离得到,分别是(7E,9R)-9-hydroxy-5,7-megastigmadien-4-one-9-O-α-L-arabinopyranosyl-(1→6)-β-Dglucopyanoside(1),(6R,7E,9R)-9-hydroxy-4,7-megastigmadien-3-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside(2),urolignoside(3),4,9,9'-trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan-7-O-β-D-glucopyranoside(4),citroside A(5),红景天苷(6),和腺苷(7)。结论:化合物1为新化合物。

Abstract: AIM:To study the chemical constituents of the aerial parts of Cirsium setosum(Willd.) MB.METHODS:The chemical constituents were isolated and purified by various chromatographic techniques.Their structures were determined on the basis of physical properties and spectroscopic data.RESULTS:A new megastigmane glycoside and six known compounds were obtained and identified as(7E,9R)-9-hydroxy-5,7-megastigmadien-4-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyanoside(1),(6R,7E,9R)-9-hydroxy-4,7-megastigmadien-3-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside(2),urolignoside(3),4,9,9'-trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan-7-O-β-D-glucopyranoside(4),citroside A(5),salidrosidin(6),and adenosine(7).CONCLUSION:Compound 1 is a new megastigmane glycoside,named as Xiaojiglycoside A.