闹羊花中的两个新化合物

Two new compounds from the flowers of Rhododendron molle

摘要: 目的:研究中药闹羊花中的化学成分。方法:运用多种色谱方法进行分离和纯化,采用IR,UV,MS和1D,2D NMR技术进行结构解析。结果:从乙醇提取物中分得2个化合物,推定其结构分别为2α,10α-环氧-3β,5β,6β,14β,16α-五羟基-木藜烷和2,6-二羟基苯甲酸苯甲酯-6-O-α-L-鼠李糖基-(1→3)-β-D-葡萄糖苷。结论:两个化合物均为新化合物。

Abstract: AIM:To study the chemical constituents of the flowers of Rhododendron molle.METHODS:Compounds were isolated by repeated chromatography over silica gel and Sephadex LH-20.Structures were elucidated based on spectral techniques,mainly 1D-and 2D-NMR and mass spectrometric analyses.RESULTS:Two compounds(1 and 2) were isolated.CONCLUSIONS:Compounds 1 and 2 were identified as two new compounds:2α,10α-epoxy-3β,5β,6β,14β,16α-hexahydroxy-grayanane and benzyl 2,6-dihydroxybenzoate-6-O-α-L-rhamnopyranosyl-(1→3)-β-D-glucopyranoside,respectively.