岗梅根中一个新的三萜皂苷

A new triterpenoid glycoside from the roots of Ilex asprella

摘要: 目的:研究岗梅根的化学成分。方法:采用硅胶、反相硅胶、Sephadex LH-20等柱色谱法对岗梅根的化学成分进行分离纯化,应用谱学技术和化学方法鉴定化合物的结构。结果:从岗梅根中分离并鉴定了4个三萜苷类化合物:(3)-19-hydroxy-28-oxours-12-en-3-yl -D-glucopyranosiduronic acid n-butyl ester(1),ilexasoside A(2),Monepaloside F(3)和ilexoside A(4)。结论:化合物1为新化合物,化合物3和4为首次从该植物中分离得到。

Abstract: AIM:To study the chemical constituents of the roots of Ilex asprella Champ.ex Benth.METHODS:Compounds were isolated by silica gel,ODS,and Sephadex LH-20 column chromatography,and their structures were elucidated on the basis of physicochemical properties and spectroscopic analysis.RESULTS:Four triterpenoid glycosides were isolated and identified as(3)-19-hydroxy-28-oxours-12-en-3-yl -D-glucopyranosiduronic acid n-butyl ester(1),ilexasoside A(2),monepaloside F(3),and ilexoside A(4).CONCLUSION:Compound 1 is a new triterpenoid glycoside,and compounds 3 and 4 were isolated from this plant for the first time.