皂帽花中的一个新生物碱

A new aristolactam alkaloid from the stems of Dasymaschalon trichophorum

摘要: 目的:对皂帽花化学成分的研究。方法:运用柱层析等方法分离纯化化合物,通过波谱解析和理化鉴别进行结构鉴定。结果:从皂帽花中分离得到5个生物碱,分别是:10-amino-3,6-dihydroxy-2,4-dimethoxyphenanthrene-1-carboxylic acid lactam(1),enterocarpam-Ⅱ(2),oldhamactam(3),goniopedaline(4)和stigmalactam(5)。结论:化合物1为新化合物,化合物2~5均为首次从该属植物中分离得到。

Abstract: AIM:To study the chemical constituents of the stem of Dasymaschaon trichophorum Merr.METHODS:The compounds were isolated and purified by the methods of various chromatography.Their structures were elucidated on the basis of spectroscopic methods.RESULTS:Five aristolactam alkaloids were obtained and their structures were identified as 10-amino-3,6-dihydroxy-2,4-dimethoxyphenanthrene-1-carboxylic acid lactam(1),enterocarpam-Ⅱ(2),oldhamactam(3),goniopedaline(4),and stigmalactam(5),respectively.CONCLUSION:Compound 1 is a new aristolactam alkaloid,while compounds 2-5 are reported from this genus for the first time.