尖瓣光萼苔(东亚亚种)中的一个新愈创木烷型倍半萜内酯化合物

A new guaiane-type sesquiterpene lactone from the Chinese liverwort Porella acutifolia subsp. tosana

摘要: 目的:研究中国尖瓣光萼苔(东亚亚种)的化学成分。方法:采用多种柱色谱技术分离,运用NMR、MS、IR等多种波谱技术鉴定化合物的结构。结果:从尖瓣光萼苔(东亚亚种)中分离得到3个化合物,分别为guaian-3-en-2,14-6,12-diolide(1)、(20R)-6-hydroxystigmasta-4,22-dien-3-one(2)和(20R)-3-hydroxystigmasta-5,22-dien-7-one(3)。结论:化合物1为新化合物,化合物2和3为已知甾体。

Abstract: AIM:To study the chemical constituents of the Chinese liverwort Porella acutifolia subsp.tosana.METHODS:The compounds were isolated and purified with column chromatography and their structures were determined on the basis of 1D-and 2D-NMR analysis.RESULTS:Three compounds were obtained and identified as guaian-3-en-2,14-6,12-diolide(1),(20R)-6-hydroxystigmasta-4,22-dien-3-one(2),and(20R)-3-hydroxystigmasta-5,22-dien-7-one(3).CONCLUSION:Compound 1 is a new guaiane-type sesquiterpene lactone.Compounds 2 and 3 are known steroids.