杏鲍菇中一个新的薄荷烷型单萜

A new menthane-type monoterpene from Pleurotus eryngii

摘要: 对侧耳属真菌杏鲍菇(Pleurotus eryngii)的发酵液进行了系统的化学成分研究,经过一系列的正相反相硅胶柱色谱和高效液相色谱等现代分离技术,分离得到2个薄荷烷型单萜、3个麦角甾醇和1个脑苷酯B,并通过MS,IR,NMR等光谱学方法确定了这些化合物的结构。其中侧耳内酯(1)为一个新的薄荷烷型单萜。

Abstract: A new menthane-type monoterpene,pleurolactone(1),was isolated from the culture broth of the fungus Pleurotus eryngii,along with five known compounds 1,2-dihydroxymintlactone(2),(22E,24R)-ergosta-5,7,22-trien-3-ol(3),(22E,24R)-ergosta-7,22-dien-3,5,6-triol(4),(22E,24R)-ergosta-7,22-dien-3-ol(5),and cerebroside B(6).Their structures were identified by extensive spectroscopic analyses.