狼毒大戟的化学成分
Chemical constituents of Euphorbia fischeriana
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摘要: 目的:研究狼毒大戟根的化学成分。方法:用多种层析方法对化合物进行分离纯化,根据光谱数据和理化性质鉴定结构。结果:分离并鉴定了11个化合物,即(+)-nyasol (1), 23(Z)-环阿尔廷-23-烯-3, 25-二醇(2),环阿尔廷-22-烯-3, 25-二醇(3),月腺大戟素A (4), 2, 4-二羟基-6-甲氧基-3-醛基苯乙酮(5), -亚麻酸(6), 24-亚甲基环木菠萝烷醇(7),环阿尔廷醇(8), -谷甾醇(9), 3, 3'-二乙酰基-4, 4'-二甲氧基-2, 2', 6, 6'-四羟基二苯甲烷(10),狼毒乙素(11)。结论:化合物1为该属首次分离,化合物2-6为该种植物首次分离。Abstract: AIM: To investigate the chemical constituents in the roots of Euphorbia fischeriana. METHODS: The chemical constituents were isolated and purified by various chromatographic techniques. Their structures were identified on the basis of spectroscopic analyses and physiochemical properties. RESULTS: Eleven compounds were isolated and elucidated as (+)-nyasol (1), 23(Z)-cycloart-23-en-3, 25-diol (2), cycloart-22-ene-3, 25-diol (3), ebracteolatain A (4), 2, 4-dihydroxy-6-methoxy-3-formyl-1- acetophenone (5), -linolenic acid (6), 24-methylenecycloartanol (7), cycloartenol (8), -sitosterol (9), 3, 3'-diacetyl-4, 4'-dimethoxy-2, 2', 6, 6'-tetrahydroxy diphenylmethane (10), 2, 4-dihydroxy-6-methoxy-3-methyl-1-acetophenone (11). CONCLUSION: Compound 1 was found in the genus Euphorbia for the first time and compounds 2-6 were firstly isolated from Euphorbia fischeriana.
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