大飞扬草地上部位的酚类和黄酮类化合物

Phenols and flavonoids from the aerial part of Euphorbia hirta

摘要: 目的:研究大飞扬草地上部分的化学成分,为研究其药理作用提供物质依据。方法:采用硅胶、大孔树脂、凝胶等柱层析方法,从大飞扬草地上部分分离得到化合物,并通过波谱方法确定其化学结构。结果:这些化合物分别是:东莨菪亭(1)、滨蒿内酯(2)、异东莨菪亭(3)、槲皮素(4)、异鼠李素(5)、乔松素(6)、山奈酚(7)、木犀草素(8)和没食子酸(9)。结论:这些化合物中, 1-3、5-8为首次从该植物中分离得到。

Abstract: AIM: To investigate the chemical constituents of the aerial part of Euphorbia hirta Linn. METHODS: The chemical constituents were isolated and purified by various chromatographic techniques, and their structures were elucidated on the basis of spectroscopic analysis. RESULTS: Nine compounds were isolated and identified as scopoletin (1), scoparone (2), isoscopoletin (3), quercetin (4), isorhamnetin (5), pinocembrin (6), kaempferol (7), luteolin (8), gallic acid (9). CONCLUSION: Among them compounds 1-3, 5-8 were found from this plant for the first time.