鸡血藤的化学成分
Chemical constituents of Spatholobus suberectus
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摘要: 目的:研究鸡血藤的化学成分。方法:利用各种层析方法分离和纯化,并利用光谱学和理化性质来鉴定化合物结构。结果:从中分离得到17个化合物,分别鉴定为prestegane B(1),(2R, 3R)-buteaspermanol(2),(+)-medioresinol(3),(2R, 3R)-3,7-dihydroxyflavanone(4), benzeneethanol(5), 4, 7, 2'-trihydroxy-4'-methoxyisoflavanol(6), naringenin(7), blumenol A(8), protocatechuicacid ethyl ester(9), liquiritigenin(10), 7, 4'-dihydroxy-8-methoxy-isoflavone(11), 3, 5, 7, 3', 5'-pentahydroxyflavanone(12), protocatechuicacid(13), glycyroside(14), 8-methylretusin-7-O--D-glucopyranoside(15), 3, 3', 4', 5, 6, 7, 8-heptahydroxyflavan(16), dulcisflavan(17)。结论:所有的化合物均为首次从该植物中分离得到,其中1, 3为首次从该属植物中分离得到。Abstract: AIM: To investigate chemical constituents of Spatholobus suberectus Dunn. METHODS: Isolation and purification were carried out by column chromatographic methods. Compounds were characterized based on their physical characteristics and spectra data. RESULTS: Seventeen compounds were isolated from ethanol extract of S. suberectus. The structures were elucidated as prestegane B (1), (2R, 3R)-buteaspermanol (2), (+)-medioresinol (3), (2R, 3R)-3,7-dihydroxyflavanone (4), benzeneethanol (5), 4, 7, 2'-trihydroxy-4'-methoxyisoflavanol (6), naringenin (7), blumenol A (8), protocatechuic acid ethyl ester (9), liquiritigenin (10), 7, 4'-dihydroxy-8-methoxy-isoflavone (11), 3, 5, 7, 3', 5'-pentahydroxyflavanone (12), protocatechuic acid (13), glycyroside (14), 8-methylretusin-7-O--D-glucopyranoside (15), 3, 3', 4', 5, 6, 7, 8-heptahydroxyflavan (16), and dulcisflavan (17). CONCLUSION: All compounds are firstly isolated from the title plant and compounds 1, 3 were isolated from the Spatholobus genus for the first time.