密脉鹅掌柴中两个新的羽扇豆烷型三萜

Two new lupane triterpenoides from Schefflera venulosa

摘要: 目的:对密脉鹅掌柴的化学成分进行研究。方法:采用硅胶柱色谱、Rp-C8柱色谱等方法分离化学成分,应用UV、IR、MS、NMR、2D-NMR等方法进行结构分析。结果:从密脉鹅掌柴中分离鉴定了2个新的化合物:3-O--D-吡喃葡萄糖醛酸基-14-醛基-白桦脂酸苷-28-O--D-吡喃葡萄糖(1), 3-O--D-吡喃葡萄糖基(12)--D-吡喃葡萄糖基-14-醛基-白桦脂酸苷-28-O--D-吡喃葡萄糖(2)。结论:化合物1和2为新的羽扇豆烷型三萜。

Abstract: AIM: To study the chemical constituents of Schefflera venulosa. METHODS: Compounds were isolated by silica gel and Rp-C8 column chromatography. The structures were elucidated by NMR and HRESI-MS spectrometry. RESULTS: Two new compounds were isolated from Schefflera venulosa, and their structures were elucidated as 3-O--D-glucopyranosyl-(12)--D-glucopyranosyl-27-oxo-betulinic acid-28-O--D-glucopyranoside (1), 3-O--D-glucuronopyranosyl-27-oxo-betulinic acid-28-O--D-glucopyranoside (2). CONCLUSION: Compounds 1 and 2 are new lupane triterpenoids.