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Jia-Kun DAI, Duo CAO, Cui-Hua LI, Jing GAO, Meng-Qing LI, Na FAN, Ya-Hui WEI, Zheng-Liang SUN, Meng-Yang HOU. Three new bioactive flavonoid glycosides from Viscum album[J]. Chinese Journal of Natural Medicines, 2019, 17(7): 545-550.
Citation: Jia-Kun DAI, Duo CAO, Cui-Hua LI, Jing GAO, Meng-Qing LI, Na FAN, Ya-Hui WEI, Zheng-Liang SUN, Meng-Yang HOU. Three new bioactive flavonoid glycosides from Viscum album[J]. Chinese Journal of Natural Medicines, 2019, 17(7): 545-550.

Three new bioactive flavonoid glycosides from Viscum album

  • Abstract: Two new flavonoid glycosides, named viscumneoside XⅡ ( 1 ), and viscumneoside XⅢ ( 2 ); a new dihydrogen flavonoid glycoside product named viscumneoside XIV ( 3 ), were isolated from the aerial part of Viscum album, along with seven known compounds ( 4-10 ). Their structures were identified by analysis of spectroscopic data. In addition, cytotoxicity assay showed that 1 , 2 and 3 possessed significant inhibitory activities against C6, A549 and MDA-MB-231 (the inhibition rate arrived about 50%, 70% and 74% respectively with IC50 ≤ 60.00 μmol·L-1), while the inhibition of TF-1 and Hela was not significant.

     

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