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WANG Si-Xian, ZHAO Rui-Lin, GUO Cui, CHEN Bao-Song, DAI Huan-Qin, LIU Gao-Qiang, LIU Hong-Wei. New meroterpenoid compounds from the culture of mushroom Panus lecomtei [J]. Chin J Nat Med, 2020, 18(4): 268-272. doi: 10.1016/S1875-5364(20)30033-9
Citation: WANG Si-Xian, ZHAO Rui-Lin, GUO Cui, CHEN Bao-Song, DAI Huan-Qin, LIU Gao-Qiang, LIU Hong-Wei. New meroterpenoid compounds from the culture of mushroom Panus lecomtei [J]. Chin J Nat Med, 2020, 18(4): 268-272. doi: 10.1016/S1875-5364(20)30033-9
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New meroterpenoid compounds from the culture of mushroom Panus lecomtei

    摘要
  • Abstract: Two new meroterpenoid compounds ( 1 and 2 ) together with five known meroterpenoid derivatives ( 3 – 7 ) were isolated from solid culture of mushroom Panus lecomtei. The structures of new compounds were confirmed by the analysis of NMR and HR-ESI-MS spectroscopic data. The biosynthetic pathway of 1 – 7 was postulated. All isolated compounds were evaluated for antibacterial activities against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa and Bacillus Calmette–Guérin. Compound 3 exhibited weak antibacterial activity against Bacillus Calmette–Guérin with the inhibition rate of 83.6% at 100 μmol·L−1. Other compounds showed no antibacterial activities against all tested pathogens at 100 μmol·L−1.

     

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