Abstract:
Two new caryophyllene-type sesquiterpenoids, pestathenols A (
1 ) and B (
2 ) and one new
α-furanone, pestatheranone A (
6 ), along with five known compounds (
3 –
5 ,
7 and
8 ) have been isolated from the crude extract of the plant endophytic fungus
Pestalotiopsis theae. Their structures were unambiguously established by extensive spectroscopic analyses. The absolute configuration of the 5,6-diol moiety in
1 was assigned using Snatzke’s method. Compounds
1 and
2 showed weak cytotoxicity against HeLa cell line.