A new lignan glycoside from Forsythia suspensa

Phytochemical investigation on Forsythia suspensa(Thunb.) Vahl afforded ten compounds,including five lignan glycosides and five phenylethanoid glycosides.The compounds were isolated by using HP-20 macroporous resin,silica gel,octadecyl silica gel(ODS),size exclusion chromatography resin HW-40 chromatography,and preparative HPLC.The structures were established through application of extensive spectroscopic methods,including ESI-MS,1D-and 2D-NMR spectroscopy.They were identified as forsythialanside E(1),8'-hydroxypinoresinol-4'-O-β-D-glucoside(2),8'-hydroxypinoresinol(3),lariciresinol-4'-O-β-D-glucoside(4),lariciresinol-4-O-β-D-glucoside(5),forsythoside H(6),forsythoside I(7),forsythoside F(8),plantainoside B(9),and plantainoside A(10).Compound 1 was a new lignan glycoside.