Consolacion Y. Ragasa, Dinah L. Espineli, Esperanza Maribel G. Agoo, Ramon S. del Fierro. Chemical constituents of Cinnamomum cebuense[J]. Chinese Journal of Natural Medicines, 2013, 11(3): 264-268.
Citation: Consolacion Y. Ragasa, Dinah L. Espineli, Esperanza Maribel G. Agoo, Ramon S. del Fierro. Chemical constituents of Cinnamomum cebuense[J]. Chinese Journal of Natural Medicines, 2013, 11(3): 264-268.

Chemical constituents of Cinnamomum cebuense

  • AIM:To investigate the chemical constituents of Cinnamomum cebuense,an endemic and critically endangered tree found only in Cebu,Philippines.METHODS:The compounds were isolated by silica gel chromatography.The structures of the isolates were elucidated by NMR spectroscopy.RESULTS:The dichloromethane(DCM) extract of the bark of C.cebuense afforded a new monoterpene natural product 1 and a new sesquiterpene 2,along with the known compounds,4-hydroxy-3-methoxycinnamaldehyde(3),4-allyl-2-methoxyphenol(4),α-terpineol(5) and humulene(6).The DCM extract of the leaves of C.cebuense yielded 6,β-caryophyllene(7),squalene(8),and a mixture of α-amyrin(9),β-amyrin(10) and bauerenol(11).The structures of 1-7 were elucidated by extensive 1D and 2D NMR spectroscopy,while the structures of 8-11 were identified by comparison of their 13C NMR data with those reported in the literature.CONCLUSION:The bark of C.cebuense afforded monoterpenes,sesquiterpenes and phenolics,while the leaves yielded sesquiterpenes and triterpenes.
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