Two novel resin glycosides isolated from Ipomoea cairica with α-glucosidase inhibitory activity

In the present study, two new compounds from Ipomoea cairica were identified and demonstrated to have -glucosidase inhibitory activity. They were isolated by column chromatography on silica gel and sephadex LH-20 and finally purified by prep-HPLC, with their structures being elucidated by spectroscopic methods, such as 1D-and 2D-NMR and HR-TOF-MS, and chemical methods. Compounds 1 and 2, named cairicoside A and cairicoside B, were evaluated for -glucosidase inhibitory activity by the MTT method, with the IC50 values being 25.3 1.6 and 28.5 3.3 molL-1, respectively.