Geranylated or prenylated flavonoids from Cajanus volubilis
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RAO Li,
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SU Yu,
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HE Qian,
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YE Jia,
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LIU Yu,
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FAN Yue,
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HU Feng,
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ZHOU Zhen,
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GAN Lishe,
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ZHANG Yonghui,
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ZHANG Chuanrui
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Abstract
Five new flavonoid derivatives, cajavolubones A–E ( 1 – 5 ), along with six known analogues ( 6 – 11 ) were isolated from Cajanus volubilis, and their structures were elucidated by spectroscopic analysis and quantum chemical calculations. Cajavolubones A and B ( 1 and 2 ) were identified as two geranylated chalcones. Cajavolubone C ( 3 ) was a prenylated flavone, while cajavolubones D and E ( 4 and 5 ) were two prenylated isoflavanones. Compounds 3 , 8 , 9 and 11 displayed cytotoxicity against HCT-116 cancer cell line.
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