RAO Li, SU Yu, HE Qian, YE Jia, LIU Yu, FAN Yue, HU Feng, ZHOU Zhen, GAN Lishe, ZHANG Yonghui, ZHANG Chuanrui. Geranylated or prenylated flavonoids from Cajanus volubilis [J].Chin J Nat Med, 2023, 21(4): 292-297. DOI: 10.1016/S1875-5364(23)60437-6
Citation: RAO Li, SU Yu, HE Qian, YE Jia, LIU Yu, FAN Yue, HU Feng, ZHOU Zhen, GAN Lishe, ZHANG Yonghui, ZHANG Chuanrui. Geranylated or prenylated flavonoids from Cajanus volubilis [J].Chin J Nat Med, 2023, 21(4): 292-297. DOI: 10.1016/S1875-5364(23)60437-6
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Geranylated or prenylated flavonoids from Cajanus volubilis

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  • Five new flavonoid derivatives, cajavolubones A–E ( 1 – 5 ), along with six known analogues ( 6 – 11 ) were isolated from Cajanus volubilis, and their structures were elucidated by spectroscopic analysis and quantum chemical calculations. Cajavolubones A and B ( 1 and 2 ) were identified as two geranylated chalcones. Cajavolubone C ( 3 ) was a prenylated flavone, while cajavolubones D and E ( 4 and 5 ) were two prenylated isoflavanones. Compounds 3 , 8 , 9 and 11 displayed cytotoxicity against HCT-116 cancer cell line.
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